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Identification of altered protein abundances in cholesteatoma matrix via mass spectrometry-based proteomic analysis

BACKGROUND: Cholesteatoma are cyst-like structures lined with a matrix of differentiated squamous epithelium overlying connective tissue. Although epithelium normally exhibits self-limited growth, cholesteatoma matrix erodes mucosa and bone suggesting changes in matrix protein constituents that perm...

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Detalles Bibliográficos
Autores principales: Randall, Derrick R., Park, Phillip S., Chau, Justin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660678/
https://www.ncbi.nlm.nih.gov/pubmed/26608071
http://dx.doi.org/10.1186/s40463-015-0104-4