Phenotype plasticity rather than repopulation from CD90/CK14+ cancer stem cells leads to cisplatin resistance of urothelial carcinoma cell lines

BACKGROUND: Tumour heterogeneity and resistance to systemic treatment in urothelial carcinoma (UC) may arise from cancer stem cells (CSC). A recent model describes cellular differentiation states within UC based on corresponding expression of surface markers (CD) and cytokeratins (CK) with CD90 and...

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Detalles Bibliográficos
Autores principales: Skowron, Margaretha A., Niegisch, Günter, Fritz, Gerhard, Arent, Tanja, van Roermund, Joep G. H., Romano, Andrea, Albers, Peter, Schulz, Wolfgang A., Hoffmann, Michèle J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660687/
https://www.ncbi.nlm.nih.gov/pubmed/26606927
http://dx.doi.org/10.1186/s13046-015-0259-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660687/
https://www.ncbi.nlm.nih.gov/pubmed/26606927
http://dx.doi.org/10.1186/s13046-015-0259-x

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