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Comparison of short- with long-term regeneration results after digital nerve reconstruction with muscle-in-vein conduits

Muscle-in-vein conduits are used alternatively to nerve grafts for bridging nerve defects. The purpose of this study was to examine short- and long-term regeneration results after digital nerve reconstruction with muscle-in-vein conduits. Static and moving two-point discriminations and Semmes-Weinst...

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Autores principales: Schiefer, Jennifer Lynn, Schulz, Lukas, Rath, Rebekka, Stahl, Stéphane, Schaller, Hans-Eberhard, Manoli, Theodora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660764/
https://www.ncbi.nlm.nih.gov/pubmed/26692868
http://dx.doi.org/10.4103/1673-5374.165321
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author Schiefer, Jennifer Lynn
Schulz, Lukas
Rath, Rebekka
Stahl, Stéphane
Schaller, Hans-Eberhard
Manoli, Theodora
author_facet Schiefer, Jennifer Lynn
Schulz, Lukas
Rath, Rebekka
Stahl, Stéphane
Schaller, Hans-Eberhard
Manoli, Theodora
author_sort Schiefer, Jennifer Lynn
collection PubMed
description Muscle-in-vein conduits are used alternatively to nerve grafts for bridging nerve defects. The purpose of this study was to examine short- and long-term regeneration results after digital nerve reconstruction with muscle-in-vein conduits. Static and moving two-point discriminations and Semmes-Weinstein Monofilaments were used to evaluate sensory recovery 6–12 months and 14–35 months after repair of digital nerves with muscle-in-vein in 7 cases. Both follow-ups were performed after clinical signs of progressing regeneration disappeared. In 4 of 7 cases, a further recovery of both two-point discriminations and in another case of only the static two-point discrimination of 1–3 mm could be found between the short-term and long-term follow-up examination. Moreover, a late recovery of both two-point discriminations was demonstrated in another case. Four of 7 cases showed a sensory improvement by one Semmes-Weinstein Monofilaments. This pilot study suggests that sensory recovery still takes place even when clinical signs of progressing regeneration disappear.
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spelling pubmed-46607642015-12-11 Comparison of short- with long-term regeneration results after digital nerve reconstruction with muscle-in-vein conduits Schiefer, Jennifer Lynn Schulz, Lukas Rath, Rebekka Stahl, Stéphane Schaller, Hans-Eberhard Manoli, Theodora Neural Regen Res Research Article Muscle-in-vein conduits are used alternatively to nerve grafts for bridging nerve defects. The purpose of this study was to examine short- and long-term regeneration results after digital nerve reconstruction with muscle-in-vein conduits. Static and moving two-point discriminations and Semmes-Weinstein Monofilaments were used to evaluate sensory recovery 6–12 months and 14–35 months after repair of digital nerves with muscle-in-vein in 7 cases. Both follow-ups were performed after clinical signs of progressing regeneration disappeared. In 4 of 7 cases, a further recovery of both two-point discriminations and in another case of only the static two-point discrimination of 1–3 mm could be found between the short-term and long-term follow-up examination. Moreover, a late recovery of both two-point discriminations was demonstrated in another case. Four of 7 cases showed a sensory improvement by one Semmes-Weinstein Monofilaments. This pilot study suggests that sensory recovery still takes place even when clinical signs of progressing regeneration disappear. Medknow Publications & Media Pvt Ltd 2015-10 /pmc/articles/PMC4660764/ /pubmed/26692868 http://dx.doi.org/10.4103/1673-5374.165321 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Research Article
Schiefer, Jennifer Lynn
Schulz, Lukas
Rath, Rebekka
Stahl, Stéphane
Schaller, Hans-Eberhard
Manoli, Theodora
Comparison of short- with long-term regeneration results after digital nerve reconstruction with muscle-in-vein conduits
title Comparison of short- with long-term regeneration results after digital nerve reconstruction with muscle-in-vein conduits
title_full Comparison of short- with long-term regeneration results after digital nerve reconstruction with muscle-in-vein conduits
title_fullStr Comparison of short- with long-term regeneration results after digital nerve reconstruction with muscle-in-vein conduits
title_full_unstemmed Comparison of short- with long-term regeneration results after digital nerve reconstruction with muscle-in-vein conduits
title_short Comparison of short- with long-term regeneration results after digital nerve reconstruction with muscle-in-vein conduits
title_sort comparison of short- with long-term regeneration results after digital nerve reconstruction with muscle-in-vein conduits
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660764/
https://www.ncbi.nlm.nih.gov/pubmed/26692868
http://dx.doi.org/10.4103/1673-5374.165321
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