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Cytochrome P450 125A4, the Third Cholesterol C-26 Hydroxylase from Mycobacterium smegmatis
[Image: see text] Mycobacterium tuberculosis (Mtb) and Mycobacterium smegmatis (Msmeg) can grow on cholesterol as the sole carbon source. In Mtb the utilization of cholesterol can be initiated by CYP125A1 or CYP142A1 and in Msmeg by the orthologous CYP125A3 and CYP142A2. Double knockout of the two e...
Autores principales: | Frank, Daniel J., Waddling, Christopher A., La, Maggie, Ortiz de Montellano, Paul R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660985/ https://www.ncbi.nlm.nih.gov/pubmed/26522442 http://dx.doi.org/10.1021/acs.biochem.5b01029 |
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