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Synthesis, antimicrobial and cytotoxicity evaluation of new cholesterol congeners

3β-Azidocholest-5-ene (3) and (3β)-3-(prop-2-yn-1-yloxy)cholest-5-ene (10) were prepared as substrates to synthesize a variety of three-motif pharmacophoric conjugates through CuAAC. Basically, these conjugates included cholesterol and 1,2,3-triazole moieties, while the third, the pharmacophore, was...

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Detalles Bibliográficos
Autores principales:	Aly, Mohamed Ramadan El Sayed, Saad, Hosam Ali, Abdel-Hafez, Shams Hashim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2015
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661006/ https://www.ncbi.nlm.nih.gov/pubmed/26664612 http://dx.doi.org/10.3762/bjoc.11.208

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