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Recurrent Streptococcus Pneumoniae Meningitis in a Child with Split Hand and Foot Malformation and Undiagnosed Mondini Dysplasia

Recurrent bacterial meningitis is a life-threatening infection of the central nervous system that is mostly connected with anatomical abnormalities of the skull, chronic parameningeal infections and immunodeficiencies. It’s rarely seen, but when it occurs an extensive investigation should be carried...

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Autores principales: Katarzyna, Mazur-Melewska, Jarosław, Szydłowski, Katarzyna, Jończyk-Potoczna, Wojciech, Służewski, Magdalena, Figlerowicz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661223/
https://www.ncbi.nlm.nih.gov/pubmed/26640357
http://dx.doi.org/10.1007/s10882-015-9460-2
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author Katarzyna, Mazur-Melewska
Jarosław, Szydłowski
Katarzyna, Jończyk-Potoczna
Wojciech, Służewski
Magdalena, Figlerowicz
author_facet Katarzyna, Mazur-Melewska
Jarosław, Szydłowski
Katarzyna, Jończyk-Potoczna
Wojciech, Służewski
Magdalena, Figlerowicz
author_sort Katarzyna, Mazur-Melewska
collection PubMed
description Recurrent bacterial meningitis is a life-threatening infection of the central nervous system that is mostly connected with anatomical abnormalities of the skull, chronic parameningeal infections and immunodeficiencies. It’s rarely seen, but when it occurs an extensive investigation should be carried out to discover the responsible factor, so that further episodes can be prevented. We report on a child with split hand and foot (SHFM), confirmed incorrect karyotype 46, XY, t(7:12)(q21.2;q21.3) and a fourth episode of fulminant meningitis caused by penicillin-resistant Streptococcus pneumoniae. After a broad evaluation of factors predisposing to recurrent meningitis, the undiagnosed malformation of his inner and middle ears - Mondini dysplasia was found. We suggest examining all children with SHFM for hearing impairment before they develop recurrent meningitis. The time when the radiological procedure for searching for inner ear dysplasia should be performed could be a controversial issue: before or after the first episode of meningitis. From the epidemiological point of view, high-resolution computer tomography scanning of the temporal bones should be considered after the diagnosis of deafness in a child with SHFM related to 7q21 deletion.
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spelling pubmed-46612232015-12-04 Recurrent Streptococcus Pneumoniae Meningitis in a Child with Split Hand and Foot Malformation and Undiagnosed Mondini Dysplasia Katarzyna, Mazur-Melewska Jarosław, Szydłowski Katarzyna, Jończyk-Potoczna Wojciech, Służewski Magdalena, Figlerowicz J Dev Phys Disabil Original Article Recurrent bacterial meningitis is a life-threatening infection of the central nervous system that is mostly connected with anatomical abnormalities of the skull, chronic parameningeal infections and immunodeficiencies. It’s rarely seen, but when it occurs an extensive investigation should be carried out to discover the responsible factor, so that further episodes can be prevented. We report on a child with split hand and foot (SHFM), confirmed incorrect karyotype 46, XY, t(7:12)(q21.2;q21.3) and a fourth episode of fulminant meningitis caused by penicillin-resistant Streptococcus pneumoniae. After a broad evaluation of factors predisposing to recurrent meningitis, the undiagnosed malformation of his inner and middle ears - Mondini dysplasia was found. We suggest examining all children with SHFM for hearing impairment before they develop recurrent meningitis. The time when the radiological procedure for searching for inner ear dysplasia should be performed could be a controversial issue: before or after the first episode of meningitis. From the epidemiological point of view, high-resolution computer tomography scanning of the temporal bones should be considered after the diagnosis of deafness in a child with SHFM related to 7q21 deletion. Springer US 2015-11-12 2015 /pmc/articles/PMC4661223/ /pubmed/26640357 http://dx.doi.org/10.1007/s10882-015-9460-2 Text en © The Author(s) 2015 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Katarzyna, Mazur-Melewska
Jarosław, Szydłowski
Katarzyna, Jończyk-Potoczna
Wojciech, Służewski
Magdalena, Figlerowicz
Recurrent Streptococcus Pneumoniae Meningitis in a Child with Split Hand and Foot Malformation and Undiagnosed Mondini Dysplasia
title Recurrent Streptococcus Pneumoniae Meningitis in a Child with Split Hand and Foot Malformation and Undiagnosed Mondini Dysplasia
title_full Recurrent Streptococcus Pneumoniae Meningitis in a Child with Split Hand and Foot Malformation and Undiagnosed Mondini Dysplasia
title_fullStr Recurrent Streptococcus Pneumoniae Meningitis in a Child with Split Hand and Foot Malformation and Undiagnosed Mondini Dysplasia
title_full_unstemmed Recurrent Streptococcus Pneumoniae Meningitis in a Child with Split Hand and Foot Malformation and Undiagnosed Mondini Dysplasia
title_short Recurrent Streptococcus Pneumoniae Meningitis in a Child with Split Hand and Foot Malformation and Undiagnosed Mondini Dysplasia
title_sort recurrent streptococcus pneumoniae meningitis in a child with split hand and foot malformation and undiagnosed mondini dysplasia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661223/
https://www.ncbi.nlm.nih.gov/pubmed/26640357
http://dx.doi.org/10.1007/s10882-015-9460-2
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