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Function of desiccate in gustatory sensilla of drosophila melanogaster

Desiccate (Desi), initially discovered as a gene expressing in the epidermis of Drosophila larvae for protection from desiccation stress, was recently found to be robustly expressed in the adult labellum; however, the function, as well as precise expression sites, was unknown. Here, we found that De...

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Autores principales: Kawano, Takeshi, Ryuda, Masasuke, Matsumoto, Hitoshi, Ochiai, Masanori, Oda, Yasunori, Tanimura, Teiichi, Csikos, Gyorge, Moriya, Megumi, Hayakawa, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661605/
https://www.ncbi.nlm.nih.gov/pubmed/26610608
http://dx.doi.org/10.1038/srep17195
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author Kawano, Takeshi
Ryuda, Masasuke
Matsumoto, Hitoshi
Ochiai, Masanori
Oda, Yasunori
Tanimura, Teiichi
Csikos, Gyorge
Moriya, Megumi
Hayakawa, Yoichi
author_facet Kawano, Takeshi
Ryuda, Masasuke
Matsumoto, Hitoshi
Ochiai, Masanori
Oda, Yasunori
Tanimura, Teiichi
Csikos, Gyorge
Moriya, Megumi
Hayakawa, Yoichi
author_sort Kawano, Takeshi
collection PubMed
description Desiccate (Desi), initially discovered as a gene expressing in the epidermis of Drosophila larvae for protection from desiccation stress, was recently found to be robustly expressed in the adult labellum; however, the function, as well as precise expression sites, was unknown. Here, we found that Desi is expressed in two different types of non-neuronal cells of the labellum, the epidermis and thecogen accessory cells. Labellar Desi expression was significantly elevated under arid conditions, accompanied by an increase in water ingestion by adults. Desi overexpression also promoted water ingestion. In contrast, a knockdown of Desi expression reduced feeding as well as water ingestion due to a drastic decrease in the gustatory sensillar sensitivity for all tested tastants. These results indicate that Desi helps protect insects from desiccation damage by not only preventing dehydration through the integument but also accelerating water ingestion via elevated taste sensitivities of the sensilla.
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spelling pubmed-46616052015-12-01 Function of desiccate in gustatory sensilla of drosophila melanogaster Kawano, Takeshi Ryuda, Masasuke Matsumoto, Hitoshi Ochiai, Masanori Oda, Yasunori Tanimura, Teiichi Csikos, Gyorge Moriya, Megumi Hayakawa, Yoichi Sci Rep Article Desiccate (Desi), initially discovered as a gene expressing in the epidermis of Drosophila larvae for protection from desiccation stress, was recently found to be robustly expressed in the adult labellum; however, the function, as well as precise expression sites, was unknown. Here, we found that Desi is expressed in two different types of non-neuronal cells of the labellum, the epidermis and thecogen accessory cells. Labellar Desi expression was significantly elevated under arid conditions, accompanied by an increase in water ingestion by adults. Desi overexpression also promoted water ingestion. In contrast, a knockdown of Desi expression reduced feeding as well as water ingestion due to a drastic decrease in the gustatory sensillar sensitivity for all tested tastants. These results indicate that Desi helps protect insects from desiccation damage by not only preventing dehydration through the integument but also accelerating water ingestion via elevated taste sensitivities of the sensilla. Nature Publishing Group 2015-11-27 /pmc/articles/PMC4661605/ /pubmed/26610608 http://dx.doi.org/10.1038/srep17195 Text en Copyright © 2015, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Kawano, Takeshi
Ryuda, Masasuke
Matsumoto, Hitoshi
Ochiai, Masanori
Oda, Yasunori
Tanimura, Teiichi
Csikos, Gyorge
Moriya, Megumi
Hayakawa, Yoichi
Function of desiccate in gustatory sensilla of drosophila melanogaster
title Function of desiccate in gustatory sensilla of drosophila melanogaster
title_full Function of desiccate in gustatory sensilla of drosophila melanogaster
title_fullStr Function of desiccate in gustatory sensilla of drosophila melanogaster
title_full_unstemmed Function of desiccate in gustatory sensilla of drosophila melanogaster
title_short Function of desiccate in gustatory sensilla of drosophila melanogaster
title_sort function of desiccate in gustatory sensilla of drosophila melanogaster
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661605/
https://www.ncbi.nlm.nih.gov/pubmed/26610608
http://dx.doi.org/10.1038/srep17195
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