Delivery of cell-penetrating peptide-peptide nucleic acid conjugates by assembly on an oligonucleotide scaffold

Delivery to intracellular target sites is still one of the main obstacles in the development of peptide nucleic acids (PNAs) as antisense-antigene therapeutics. Here, we designed a self-assembled oligonucleotide scaffold that included a central complementary region for self-assembly and lateral regi...

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Detalles Bibliográficos
Autores principales: Zhao, Xing-Liang, Chen, Bi-Cheng, Han, Jin-Chao, Wei, Lai, Pan, Xiao-Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661726/
https://www.ncbi.nlm.nih.gov/pubmed/26612536
http://dx.doi.org/10.1038/srep17640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661726/
https://www.ncbi.nlm.nih.gov/pubmed/26612536
http://dx.doi.org/10.1038/srep17640

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