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Application of CRISPR/Cas9 Technology to HBV

More than 240 million people around the world are chronically infected with hepatitis B virus (HBV). Nucleos(t)ide analogs and interferon are the only two families of drugs to treat HBV currently. However, none of these anti-virals directly target the stable nuclear covalently closed circular DNA (c...

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Detalles Bibliográficos
Autores principales:	Lin, Guigao, Zhang, Kuo, Li, Jinming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661809/ https://www.ncbi.nlm.nih.gov/pubmed/26540039 http://dx.doi.org/10.3390/ijms161125950

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