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Betulinyl Sulfamates as Anticancer Agents and Radiosensitizers in Human Breast Cancer Cells

Betulinic acid (BA), a natural compound of birch bark, is cytotoxic for many tumors. Recently, a betulinyl sulfamate was described that inhibits carbonic anhydrases (CA), such as CAIX, an attractive target for tumor-selective therapy strategies in hypoxic cancer cells. Data on combined CAIX inhibiti...

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Detalles Bibliográficos
Autores principales: Bache, Matthias, Münch, Christin, Güttler, Antje, Wichmann, Henri, Theuerkorn, Katharina, Emmerich, Daniel, Paschke, Reinhard, Vordermark, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661812/
https://www.ncbi.nlm.nih.gov/pubmed/26540049
http://dx.doi.org/10.3390/ijms161125953

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