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Identification of Arsenic Direct-Binding Proteins in Acute Promyelocytic Leukaemia Cells

The identification of arsenic direct-binding proteins is essential for determining the mechanism by which arsenic trioxide achieves its chemotherapeutic effects. At least two cysteines close together in the amino acid sequence are crucial to the binding of arsenic and essential to the identification...

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Detalles Bibliográficos
Autores principales: Zhang, Tao, Lu, Haojie, Li, Weijun, Hu, Ronggui, Chen, Zi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661853/
https://www.ncbi.nlm.nih.gov/pubmed/26569224
http://dx.doi.org/10.3390/ijms161125994