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Targeting Mitochondrial Function to Treat Quiescent Tumor Cells in Solid Tumors
The disorganized nature of tumor vasculature results in the generation of microenvironments characterized by nutrient starvation, hypoxia and accumulation of acidic metabolites. Tumor cell populations in such areas are often slowly proliferating and thus refractory to chemotherapeutical drugs that a...
Autores principales: | Zhang, Xiaonan, de Milito, Angelo, Olofsson, Maria Hägg, Gullbo, Joachim, D’Arcy, Padraig, Linder, Stig |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661878/ https://www.ncbi.nlm.nih.gov/pubmed/26580606 http://dx.doi.org/10.3390/ijms161126020 |
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