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Prostate Cancer Stem Cells: Research Advances

Cancer stem cells have been defined as cells within a tumor that possesses the capacity to self-renew and to cause the heterogeneous lineages of cancer cells that comprise the tumor. Experimental evidence showed that these highly tumorigenic cells might be responsible for initiation and progression...

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Detalles Bibliográficos
Autores principales: Jaworska, Dagmara, Król, Wojciech, Szliszka, Ewelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661894/
https://www.ncbi.nlm.nih.gov/pubmed/26593898
http://dx.doi.org/10.3390/ijms161126036
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author Jaworska, Dagmara
Król, Wojciech
Szliszka, Ewelina
author_facet Jaworska, Dagmara
Król, Wojciech
Szliszka, Ewelina
author_sort Jaworska, Dagmara
collection PubMed
description Cancer stem cells have been defined as cells within a tumor that possesses the capacity to self-renew and to cause the heterogeneous lineages of cancer cells that comprise the tumor. Experimental evidence showed that these highly tumorigenic cells might be responsible for initiation and progression of cancer into invasive and metastatic disease. Eradicating prostate cancer stem cells, the root of the problem, has been considered as a promising target in prostate cancer treatment to improve the prognosis for patients with advanced stages of the disease.
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spelling pubmed-46618942015-12-10 Prostate Cancer Stem Cells: Research Advances Jaworska, Dagmara Król, Wojciech Szliszka, Ewelina Int J Mol Sci Review Cancer stem cells have been defined as cells within a tumor that possesses the capacity to self-renew and to cause the heterogeneous lineages of cancer cells that comprise the tumor. Experimental evidence showed that these highly tumorigenic cells might be responsible for initiation and progression of cancer into invasive and metastatic disease. Eradicating prostate cancer stem cells, the root of the problem, has been considered as a promising target in prostate cancer treatment to improve the prognosis for patients with advanced stages of the disease. MDPI 2015-11-17 /pmc/articles/PMC4661894/ /pubmed/26593898 http://dx.doi.org/10.3390/ijms161126036 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Jaworska, Dagmara
Król, Wojciech
Szliszka, Ewelina
Prostate Cancer Stem Cells: Research Advances
title Prostate Cancer Stem Cells: Research Advances
title_full Prostate Cancer Stem Cells: Research Advances
title_fullStr Prostate Cancer Stem Cells: Research Advances
title_full_unstemmed Prostate Cancer Stem Cells: Research Advances
title_short Prostate Cancer Stem Cells: Research Advances
title_sort prostate cancer stem cells: research advances
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661894/
https://www.ncbi.nlm.nih.gov/pubmed/26593898
http://dx.doi.org/10.3390/ijms161126036
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