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Prostate Cancer Stem Cells: Research Advances
Cancer stem cells have been defined as cells within a tumor that possesses the capacity to self-renew and to cause the heterogeneous lineages of cancer cells that comprise the tumor. Experimental evidence showed that these highly tumorigenic cells might be responsible for initiation and progression...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661894/ https://www.ncbi.nlm.nih.gov/pubmed/26593898 http://dx.doi.org/10.3390/ijms161126036 |
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author | Jaworska, Dagmara Król, Wojciech Szliszka, Ewelina |
author_facet | Jaworska, Dagmara Król, Wojciech Szliszka, Ewelina |
author_sort | Jaworska, Dagmara |
collection | PubMed |
description | Cancer stem cells have been defined as cells within a tumor that possesses the capacity to self-renew and to cause the heterogeneous lineages of cancer cells that comprise the tumor. Experimental evidence showed that these highly tumorigenic cells might be responsible for initiation and progression of cancer into invasive and metastatic disease. Eradicating prostate cancer stem cells, the root of the problem, has been considered as a promising target in prostate cancer treatment to improve the prognosis for patients with advanced stages of the disease. |
format | Online Article Text |
id | pubmed-4661894 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-46618942015-12-10 Prostate Cancer Stem Cells: Research Advances Jaworska, Dagmara Król, Wojciech Szliszka, Ewelina Int J Mol Sci Review Cancer stem cells have been defined as cells within a tumor that possesses the capacity to self-renew and to cause the heterogeneous lineages of cancer cells that comprise the tumor. Experimental evidence showed that these highly tumorigenic cells might be responsible for initiation and progression of cancer into invasive and metastatic disease. Eradicating prostate cancer stem cells, the root of the problem, has been considered as a promising target in prostate cancer treatment to improve the prognosis for patients with advanced stages of the disease. MDPI 2015-11-17 /pmc/articles/PMC4661894/ /pubmed/26593898 http://dx.doi.org/10.3390/ijms161126036 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Jaworska, Dagmara Król, Wojciech Szliszka, Ewelina Prostate Cancer Stem Cells: Research Advances |
title | Prostate Cancer Stem Cells: Research Advances |
title_full | Prostate Cancer Stem Cells: Research Advances |
title_fullStr | Prostate Cancer Stem Cells: Research Advances |
title_full_unstemmed | Prostate Cancer Stem Cells: Research Advances |
title_short | Prostate Cancer Stem Cells: Research Advances |
title_sort | prostate cancer stem cells: research advances |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661894/ https://www.ncbi.nlm.nih.gov/pubmed/26593898 http://dx.doi.org/10.3390/ijms161126036 |
work_keys_str_mv | AT jaworskadagmara prostatecancerstemcellsresearchadvances AT krolwojciech prostatecancerstemcellsresearchadvances AT szliszkaewelina prostatecancerstemcellsresearchadvances |