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Identification of low abundance microbiome in clinical samples using whole genome sequencing
Identifying the microbiome composition from primary tissues directly affords an opportunity to study the causative relationships between the host microbiome and disease. However, this is challenging due the low abundance of microbial DNA relative to the host. We present a systematic evaluation of mi...
Autores principales: | Zhang, Chao, Cleveland, Kyle, Schnoll-Sussman, Felice, McClure, Bridget, Bigg, Michelle, Thakkar, Prashant, Schultz, Nikolaus, Shah, Manish A., Betel, Doron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661937/ https://www.ncbi.nlm.nih.gov/pubmed/26614063 http://dx.doi.org/10.1186/s13059-015-0821-z |
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