Resources for the design of CRISPR gene editing experiments

CRISPR-based approaches have quickly become a favored method to perturb genes to uncover their functions. Here, we review the key considerations in the design of genome editing experiments, and survey the tools and resources currently available to assist users of this technology.

Detalles Bibliográficos
Autores principales: Graham, Daniel B., Root, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661947/
https://www.ncbi.nlm.nih.gov/pubmed/26612492
http://dx.doi.org/10.1186/s13059-015-0823-x
Descripción
Sumario:CRISPR-based approaches have quickly become a favored method to perturb genes to uncover their functions. Here, we review the key considerations in the design of genome editing experiments, and survey the tools and resources currently available to assist users of this technology.

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