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Physiological Characteristics and Anti-obesity Effect of Lactobacillus plantarum Q180 Isolated from Feces

Obesity is strongly associated with several metabolic and chronic diseases and has become a major public health problem of worldwide concern. This study aimed to investigate the physiological characteristics and anti-obesity effects of Lactobacillus plantarum Q180. Lactobacillus plantarum Q180 was i...

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Autores principales: Park, Sun-Young, Cho, Seong-A, Kim, Sae-Hun, Lim, Sang-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Food Science of Animal Resources 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662227/
https://www.ncbi.nlm.nih.gov/pubmed/26761499
http://dx.doi.org/10.5851/kosfa.2014.34.5.647
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author Park, Sun-Young
Cho, Seong-A
Kim, Sae-Hun
Lim, Sang-Dong
author_facet Park, Sun-Young
Cho, Seong-A
Kim, Sae-Hun
Lim, Sang-Dong
author_sort Park, Sun-Young
collection PubMed
description Obesity is strongly associated with several metabolic and chronic diseases and has become a major public health problem of worldwide concern. This study aimed to investigate the physiological characteristics and anti-obesity effects of Lactobacillus plantarum Q180. Lactobacillus plantarum Q180 was isolated from the faces of healthy adults and found to have a lipase inhibitory activity of 83.61±2.32% and inhibited adipocyte differentiation of 3T3-L1 cells (14.63±1.37%) at a concentration of 100 μg/mL. The strain was investigated for its physiological characteristics. The optimum growth temperature of L. plantarum Q180 was 37℃. Lactobacillus plantarum Q180 showed higher sensitivity to novobiocin in a comparison of fifteen different antibiotics and showed the highest resistance to rifampicin, polymyxin B and vancomycin. The strain showed higher β-galactosidase and N-acetyl-β-glucosaminidase activities. It also did not produce carcinogenic enzymes such as β-glucuronidase. The survival rate of L. plantarum Q180 in MRS broth containing 0.3% bile was 97.8%. Moreover, the strain showed a 97.2% survival rate after incubation for 3 h in pH 2.0. Lactobacillus plantarum Q180 was displayed resistance to Escherichia coli, Salmonella Typhimurium and Staphylococcus aureus with rates of 55.6%, 38.0% and 47.6%, respectively. These results demonstrate that L. plantarum Q180 has potential as a probiotic with anti-obesity effects.
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spelling pubmed-46622272016-01-04 Physiological Characteristics and Anti-obesity Effect of Lactobacillus plantarum Q180 Isolated from Feces Park, Sun-Young Cho, Seong-A Kim, Sae-Hun Lim, Sang-Dong Korean J Food Sci Anim Resour Article Obesity is strongly associated with several metabolic and chronic diseases and has become a major public health problem of worldwide concern. This study aimed to investigate the physiological characteristics and anti-obesity effects of Lactobacillus plantarum Q180. Lactobacillus plantarum Q180 was isolated from the faces of healthy adults and found to have a lipase inhibitory activity of 83.61±2.32% and inhibited adipocyte differentiation of 3T3-L1 cells (14.63±1.37%) at a concentration of 100 μg/mL. The strain was investigated for its physiological characteristics. The optimum growth temperature of L. plantarum Q180 was 37℃. Lactobacillus plantarum Q180 showed higher sensitivity to novobiocin in a comparison of fifteen different antibiotics and showed the highest resistance to rifampicin, polymyxin B and vancomycin. The strain showed higher β-galactosidase and N-acetyl-β-glucosaminidase activities. It also did not produce carcinogenic enzymes such as β-glucuronidase. The survival rate of L. plantarum Q180 in MRS broth containing 0.3% bile was 97.8%. Moreover, the strain showed a 97.2% survival rate after incubation for 3 h in pH 2.0. Lactobacillus plantarum Q180 was displayed resistance to Escherichia coli, Salmonella Typhimurium and Staphylococcus aureus with rates of 55.6%, 38.0% and 47.6%, respectively. These results demonstrate that L. plantarum Q180 has potential as a probiotic with anti-obesity effects. Korean Society for Food Science of Animal Resources 2014 2014-10-31 /pmc/articles/PMC4662227/ /pubmed/26761499 http://dx.doi.org/10.5851/kosfa.2014.34.5.647 Text en Copyright © 2014, Korean Society for Food Science of Animal Resources http://creativecommons.org/licences/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licences/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Park, Sun-Young
Cho, Seong-A
Kim, Sae-Hun
Lim, Sang-Dong
Physiological Characteristics and Anti-obesity Effect of Lactobacillus plantarum Q180 Isolated from Feces
title Physiological Characteristics and Anti-obesity Effect of Lactobacillus plantarum Q180 Isolated from Feces
title_full Physiological Characteristics and Anti-obesity Effect of Lactobacillus plantarum Q180 Isolated from Feces
title_fullStr Physiological Characteristics and Anti-obesity Effect of Lactobacillus plantarum Q180 Isolated from Feces
title_full_unstemmed Physiological Characteristics and Anti-obesity Effect of Lactobacillus plantarum Q180 Isolated from Feces
title_short Physiological Characteristics and Anti-obesity Effect of Lactobacillus plantarum Q180 Isolated from Feces
title_sort physiological characteristics and anti-obesity effect of lactobacillus plantarum q180 isolated from feces
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662227/
https://www.ncbi.nlm.nih.gov/pubmed/26761499
http://dx.doi.org/10.5851/kosfa.2014.34.5.647
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