microRNA-4717 differentially interacts with its polymorphic target in the PD1 3′ untranslated region: A mechanism for regulating PD-1 expression and function in HBV-associated liver diseases

Programmed cell death-1 (PD-1) is involved in hepatitis B virus (HBV) infection, the leading cause of hepatocellular carcinoma (HCC) worldwide. Single-nucleotide polymorphism, rs10204525, located in the PD1 3′ untranslated regions (UTR), is associated with chronic HBV infection. MicroRNAs (miRNAs) r...

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Detalles Bibliográficos
Autores principales: Zhang, Guoyu, Li, Na, Li, Zhu, Zhu, Qianqian, Li, Fang, Yang, Cuiling, Han, Qunying, Lv, Yi, Zhou, Zhihua, Liu, Zhengwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662465/
https://www.ncbi.nlm.nih.gov/pubmed/25895129

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