Mucin1 promotes the migration and invasion of hepatocellular carcinoma cells via JNK-mediated phosphorylation of Smad2 at the C-terminal and linker regions

Mucin1 (MUC1), as an oncogene, plays a key role in the progression and tumorigenesis of many human adenocarcinomas. In this study, wound-healing, transwell migration and matrigel invasion assays showed that MUC1 promotes human hepatocellular carcinoma (HCC) cell migration and invasion by MUC1 gene s...

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Detalles Bibliográficos
Autores principales: Wang, Juan, Liu, Guomu, Li, Qiongshu, Wang, Fang, Xie, Fei, Zhai, Ruiping, Guo, Yingying, Chen, Tanxiu, Zhang, Nannan, Ni, Weihua, Yuan, Hongyan, Tai, Guixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662489/
https://www.ncbi.nlm.nih.gov/pubmed/26057631

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