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Prevalence and risk factors for cervical cancer and pre-cancerous lesions in Rwanda
INTRODUCTION: Cervical cancer prevalence in Rwanda has not been well-described. Visual inspection with acetic acid or Lugol solution has been shown to be effective for cervical cancer screening in low resource settings. The aim of the study is to understand the prevalence and risk factors for cervic...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662515/ https://www.ncbi.nlm.nih.gov/pubmed/26664527 http://dx.doi.org/10.11604/pamj.2015.22.26.7116 |
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author | Makuza, Jean Damascène Nsanzimana, Sabin Muhimpundu, Marie Aimee Pace, Lydia Eleanor Ntaganira, Joseph Riedel, David James |
author_facet | Makuza, Jean Damascène Nsanzimana, Sabin Muhimpundu, Marie Aimee Pace, Lydia Eleanor Ntaganira, Joseph Riedel, David James |
author_sort | Makuza, Jean Damascène |
collection | PubMed |
description | INTRODUCTION: Cervical cancer prevalence in Rwanda has not been well-described. Visual inspection with acetic acid or Lugol solution has been shown to be effective for cervical cancer screening in low resource settings. The aim of the study is to understand the prevalence and risk factors for cervical cancer and pre- cancerous lesions among Rwandan women between 30 and 50 old undergoing screening. METHODS: This cross-sectional analytical study was done in 3 districts of Rwanda from October 2010 to June 2013. Women aged 30 to 50 years screened for cervical cancer by trained doctors, nurses and midwives. Prevalence of pre-cancerous and cancerous cervical lesions was determined. Bivariate and multivariate logistic regressions were used to assess risk factors associated with cervical cancer. RESULTS: The prevalence of pre-cancer and invasive cervical cancer was 5.9% (95% CI 4.5, 7.5) and 1.7% (95% CI 0.9, 2.5), respectively. Risk factors associated with cervical cancer in multivariate analysis included initiation of sexual activity at less than 20 years (OR=1.75; 95% CI=(1.01, 3.03); being unmarried (single, divorced and widowed) (OR=3.29; 95% CI=( 1.26, 8.60)); Older age of participants (OR= 0.52; 95% CI= (0.28, 0.97)), older age at the first pregnancy (OR=2.10; 95% CI=(1.20, 3.67) and higher number of children born (OR=0.42; 95%CI =(0.23, 0.76)) were protective. CONCLUSION: Cervical cancer continues to be a public health problem in Rwanda, but screening using VIA is practical and feasible even in rural settings. |
format | Online Article Text |
id | pubmed-4662515 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-46625152015-12-10 Prevalence and risk factors for cervical cancer and pre-cancerous lesions in Rwanda Makuza, Jean Damascène Nsanzimana, Sabin Muhimpundu, Marie Aimee Pace, Lydia Eleanor Ntaganira, Joseph Riedel, David James Pan Afr Med J Research INTRODUCTION: Cervical cancer prevalence in Rwanda has not been well-described. Visual inspection with acetic acid or Lugol solution has been shown to be effective for cervical cancer screening in low resource settings. The aim of the study is to understand the prevalence and risk factors for cervical cancer and pre- cancerous lesions among Rwandan women between 30 and 50 old undergoing screening. METHODS: This cross-sectional analytical study was done in 3 districts of Rwanda from October 2010 to June 2013. Women aged 30 to 50 years screened for cervical cancer by trained doctors, nurses and midwives. Prevalence of pre-cancerous and cancerous cervical lesions was determined. Bivariate and multivariate logistic regressions were used to assess risk factors associated with cervical cancer. RESULTS: The prevalence of pre-cancer and invasive cervical cancer was 5.9% (95% CI 4.5, 7.5) and 1.7% (95% CI 0.9, 2.5), respectively. Risk factors associated with cervical cancer in multivariate analysis included initiation of sexual activity at less than 20 years (OR=1.75; 95% CI=(1.01, 3.03); being unmarried (single, divorced and widowed) (OR=3.29; 95% CI=( 1.26, 8.60)); Older age of participants (OR= 0.52; 95% CI= (0.28, 0.97)), older age at the first pregnancy (OR=2.10; 95% CI=(1.20, 3.67) and higher number of children born (OR=0.42; 95%CI =(0.23, 0.76)) were protective. CONCLUSION: Cervical cancer continues to be a public health problem in Rwanda, but screening using VIA is practical and feasible even in rural settings. The African Field Epidemiology Network 2015-09-11 /pmc/articles/PMC4662515/ /pubmed/26664527 http://dx.doi.org/10.11604/pamj.2015.22.26.7116 Text en © Jean Damascène Makuza et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Makuza, Jean Damascène Nsanzimana, Sabin Muhimpundu, Marie Aimee Pace, Lydia Eleanor Ntaganira, Joseph Riedel, David James Prevalence and risk factors for cervical cancer and pre-cancerous lesions in Rwanda |
title | Prevalence and risk factors for cervical cancer and pre-cancerous lesions in Rwanda |
title_full | Prevalence and risk factors for cervical cancer and pre-cancerous lesions in Rwanda |
title_fullStr | Prevalence and risk factors for cervical cancer and pre-cancerous lesions in Rwanda |
title_full_unstemmed | Prevalence and risk factors for cervical cancer and pre-cancerous lesions in Rwanda |
title_short | Prevalence and risk factors for cervical cancer and pre-cancerous lesions in Rwanda |
title_sort | prevalence and risk factors for cervical cancer and pre-cancerous lesions in rwanda |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662515/ https://www.ncbi.nlm.nih.gov/pubmed/26664527 http://dx.doi.org/10.11604/pamj.2015.22.26.7116 |
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