Elucidation of the CCR1- and CCR5-binding modes of MIP-1α by application of an NMR spectra reconstruction method to the transferred cross-saturation experiments

C–C chemokine receptor 1 (CCR1) and CCR5 are involved in various inflammation and immune responses, and regulate the progression of the autoimmune diseases differently. However, the number of residues identified at the binding interface was not sufficient to clarify the differences in the CCR1- and...

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Detalles Bibliográficos
Autores principales: Yoshiura, Chie, Ueda, Takumi, Kofuku, Yutaka, Matsumoto, Masahiko, Okude, Junya, Kondo, Keita, Shiraishi, Yutaro, Shimada, Ichio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662715/
https://www.ncbi.nlm.nih.gov/pubmed/26472202
http://dx.doi.org/10.1007/s10858-015-9992-x

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