Cargando…

An HLA-C amino-acid variant in addition to HLA-B*27 confers risk for ankylosing spondylitis in the Korean population

INTRODUCTION: The presence of the HLA-B*27 allele is a major risk factor for the development of ankylosing spondylitis (AS), which causes chronic inflammation of the spine and other sites. We investigated residual effects outside HLA-B within the major histocompatibility complex (MHC) region in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Kwangwoo, Bang, So-Young, Lee, Seunghun, Lee, Hye-Soon, Shim, Seung-Cheol, Kang, Young Mo, Suh, Chang-Hee, Sun, Celi, Nath, Swapan K., Bae, Sang-Cheol, Kim, Tae-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662802/
https://www.ncbi.nlm.nih.gov/pubmed/26613595
http://dx.doi.org/10.1186/s13075-015-0855-3