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Structure and function of the N‐terminal domain of the human mitochondrial calcium uniporter

The mitochondrial calcium uniporter (MCU) is responsible for mitochondrial calcium uptake and homeostasis. It is also a target for the regulation of cellular anti‐/pro‐apoptosis and necrosis by several oncogenes and tumour suppressors. Herein, we report the crystal structure of the MCU N‐terminal do...

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Detalles Bibliográficos
Autores principales: Lee, Youngjin, Min, Choon Kee, Kim, Tae Gyun, Song, Hong Ki, Lim, Yunki, Kim, Dongwook, Shin, Kahee, Kang, Moonkyung, Kang, Jung Youn, Youn, Hyung‐Seop, Lee, Jung‐Gyu, An, Jun Yop, Park, Kyoung Ryoung, Lim, Jia Jia, Kim, Ji Hun, Kim, Ji Hye, Park, Zee Yong, Kim, Yeon‐Soo, Wang, Jimin, Kim, Do Han, Eom, Soo Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662854/
https://www.ncbi.nlm.nih.gov/pubmed/26341627
http://dx.doi.org/10.15252/embr.201540436

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