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Chromatin Dynamics and the RNA Exosome Function in Concert to Regulate Transcriptional Homeostasis

The histone variant H2A.Z is a hallmark of nucleosomes flanking promoters of protein-coding genes and is often found in nucleosomes that carry lysine 56-acetylated histone H3 (H3-K56Ac), a mark that promotes replication-independent nucleosome turnover. Here, we find that H3-K56Ac promotes RNA polyme...

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Detalles Bibliográficos
Autores principales: Rege, Mayuri, Subramanian, Vidya, Zhu, Chenchen, Hsieh, Tsung-Han S., Weiner, Assaf, Friedman, Nir, Clauder-Münster, Sandra, Steinmetz, Lars M., Rando, Oliver J., Boyer, Laurie A., Peterson, Craig L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662874/
https://www.ncbi.nlm.nih.gov/pubmed/26586442
http://dx.doi.org/10.1016/j.celrep.2015.10.030

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