Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Complex in Patients with Optic Neuritis or Neuromyelitis Optica Spectrum Disorders Using Optical Coherence Tomography in a Chinese Cohort

We evaluate a cohort of optic neuritis and neuromyelitis optica (NMO) spectrum disorders patients in a territory hospital in China. The peripapillary retinal nerve fiber layer (RNFL) and macular ganglion cell complex (GCC) were measured using spectral-domain OCT after 6 months of acute onset. The re...

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Detalles Bibliográficos
Autores principales: Tian, Guohong, Li, Zhenxin, Zhao, Guixian, Feng, Chaoyi, Li, Mengwei, Huang, Yongheng, Sun, Xinghuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662994/
https://www.ncbi.nlm.nih.gov/pubmed/26649191
http://dx.doi.org/10.1155/2015/832784
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author Tian, Guohong
Li, Zhenxin
Zhao, Guixian
Feng, Chaoyi
Li, Mengwei
Huang, Yongheng
Sun, Xinghuai
author_facet Tian, Guohong
Li, Zhenxin
Zhao, Guixian
Feng, Chaoyi
Li, Mengwei
Huang, Yongheng
Sun, Xinghuai
author_sort Tian, Guohong
collection PubMed
description We evaluate a cohort of optic neuritis and neuromyelitis optica (NMO) spectrum disorders patients in a territory hospital in China. The peripapillary retinal nerve fiber layer (RNFL) and macular ganglion cell complex (GCC) were measured using spectral-domain OCT after 6 months of acute onset. The results showed that both the peripapillary RNFL and macular GCC were significantly thinner in all optic neuritis subtypes compared to controls. In addition, the recurrent optic neuritis and NMO groups showed more severe damage on the RNFL and GCC pattern.
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spelling pubmed-46629942015-12-08 Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Complex in Patients with Optic Neuritis or Neuromyelitis Optica Spectrum Disorders Using Optical Coherence Tomography in a Chinese Cohort Tian, Guohong Li, Zhenxin Zhao, Guixian Feng, Chaoyi Li, Mengwei Huang, Yongheng Sun, Xinghuai J Ophthalmol Research Article We evaluate a cohort of optic neuritis and neuromyelitis optica (NMO) spectrum disorders patients in a territory hospital in China. The peripapillary retinal nerve fiber layer (RNFL) and macular ganglion cell complex (GCC) were measured using spectral-domain OCT after 6 months of acute onset. The results showed that both the peripapillary RNFL and macular GCC were significantly thinner in all optic neuritis subtypes compared to controls. In addition, the recurrent optic neuritis and NMO groups showed more severe damage on the RNFL and GCC pattern. Hindawi Publishing Corporation 2015 2015-11-15 /pmc/articles/PMC4662994/ /pubmed/26649191 http://dx.doi.org/10.1155/2015/832784 Text en Copyright © 2015 Guohong Tian et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Tian, Guohong
Li, Zhenxin
Zhao, Guixian
Feng, Chaoyi
Li, Mengwei
Huang, Yongheng
Sun, Xinghuai
Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Complex in Patients with Optic Neuritis or Neuromyelitis Optica Spectrum Disorders Using Optical Coherence Tomography in a Chinese Cohort
title Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Complex in Patients with Optic Neuritis or Neuromyelitis Optica Spectrum Disorders Using Optical Coherence Tomography in a Chinese Cohort
title_full Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Complex in Patients with Optic Neuritis or Neuromyelitis Optica Spectrum Disorders Using Optical Coherence Tomography in a Chinese Cohort
title_fullStr Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Complex in Patients with Optic Neuritis or Neuromyelitis Optica Spectrum Disorders Using Optical Coherence Tomography in a Chinese Cohort
title_full_unstemmed Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Complex in Patients with Optic Neuritis or Neuromyelitis Optica Spectrum Disorders Using Optical Coherence Tomography in a Chinese Cohort
title_short Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Complex in Patients with Optic Neuritis or Neuromyelitis Optica Spectrum Disorders Using Optical Coherence Tomography in a Chinese Cohort
title_sort evaluation of retinal nerve fiber layer and ganglion cell complex in patients with optic neuritis or neuromyelitis optica spectrum disorders using optical coherence tomography in a chinese cohort
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662994/
https://www.ncbi.nlm.nih.gov/pubmed/26649191
http://dx.doi.org/10.1155/2015/832784
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