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Modulation of RhoA GTPase Activity Sensitizes Human Cervix Carcinoma Cells to γ-Radiation by Attenuating DNA Repair Pathways

Radiotherapy with γ-radiation is widely used in cancer treatment to induce DNA damage reducing cell proliferation and to kill tumor cells. Although RhoA GTPase overexpression/hyperactivation is observed in many malignancies, the effect of RhoA activity modulation on cancer radiosensitivity has not b...

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Detalles Bibliográficos
Autores principales:	Osaki, Juliana H., Espinha, Gisele, Magalhaes, Yuli T., Forti, Fabio L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662998/ https://www.ncbi.nlm.nih.gov/pubmed/26649141 http://dx.doi.org/10.1155/2016/6012642

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