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The Cellular Response to Oxidatively Induced DNA Damage and Polymorphism of Some DNA Repair Genes Associated with Clinicopathological Features of Bladder Cancer

Genome instability and impaired DNA repair are hallmarks of carcinogenesis. The study was aimed at evaluating the DNA damage response in H(2)O(2)-treated lymphocytes using the alkaline comet assay in bladder cancer (BC) patients as compared to clinically healthy controls, elderly persons, and indivi...

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Detalles Bibliográficos
Autores principales: Savina, Nataliya V., Nikitchenko, Nataliya V., Kuzhir, Tatyana D., Rolevich, Alexander I., Krasny, Sergei A., Goncharova, Roza I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663333/
https://www.ncbi.nlm.nih.gov/pubmed/26649138
http://dx.doi.org/10.1155/2016/5710403