Metformin suppressed the proliferation of LoVo cells and induced a time-dependent metabolic and transcriptional alteration

Metformin is a widely used anti-diabetic drug with potential anti-tumor activity. However, little is known about its global metabolic and transcriptional impacts on tumor cells. In current study, we performed a metabolic profiling on human-derived colon cancer LoVo cells treated by 10 mM metformin f...

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Detalles Bibliográficos
Autores principales: He, Jiaojiao, Wang, Ke, Zheng, Ningning, Qiu, Yunping, Xie, Guoxiang, Su, Mingming, Jia, Wei, Li, Houkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663508/
https://www.ncbi.nlm.nih.gov/pubmed/26616174
http://dx.doi.org/10.1038/srep17423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663508/
https://www.ncbi.nlm.nih.gov/pubmed/26616174
http://dx.doi.org/10.1038/srep17423

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