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Salternamide A Suppresses Hypoxia-Induced Accumulation of HIF-1α and Induces Apoptosis in Human Colorectal Cancer Cells

Hypoxia inducible factor-1α (HIF-1α) is an essential regulator of the cellular response to low oxygen concentrations, activating a broad range of genes that provide adaptive responses to oxygen deprivation. HIF-1α is overexpressed in various cancers and therefore represents a considerable chemothera...

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Detalles Bibliográficos
Autores principales:	Bach, Duc-Hiep, Kim, Seong-Hwan, Hong, Ji-Young, Park, Hyen Joo, Oh, Dong-Chan, Lee, Sang Kook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663561/ https://www.ncbi.nlm.nih.gov/pubmed/26610526 http://dx.doi.org/10.3390/md13116962

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