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Genetic dosage and position effect of small supernumerary marker chromosome (sSMC) in human sperm nuclei in infertile male patient

Chromosomes occupy specific distinct areas in the nucleus of the sperm cell that may be altered in males with disrupted spermatogenesis. Here, we present alterations in the positioning of the human chromosomes 15, 18, X and Y between spermatozoa with the small supernumerary marker chromosome (sSMC;...

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Detalles Bibliográficos
Autores principales: Olszewska, Marta, Wanowska, Elzbieta, Kishore, Archana, Huleyuk, Nataliya, Georgiadis, Andrew P., Yatsenko, Alexander N., Mikula, Mariya, Zastavna, Danuta, Wiland, Ewa, Kurpisz, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663790/
https://www.ncbi.nlm.nih.gov/pubmed/26616419
http://dx.doi.org/10.1038/srep17408