Cargando…

Therapeutic effect of baicalin on experimental autoimmune encephalomyelitis is mediated by SOCS3 regulatory pathway

Natural compounds derived from medicinal plants have long been considered a rich source of novel therapeutic agents. Baicalin (Ba) is a bioactive flavonoid compound derived from the root of Scutellaria baicalensis, an herb widely used in traditional medicine for the treatment of various inflammatory...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yuan, Li, Xing, Ciric, Bogoljub, Ma, Cun-Gen, Gran, Bruno, Rostami, Abdolmohamad, Zhang, Guang-Xian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663791/ https://www.ncbi.nlm.nih.gov/pubmed/26616302 http://dx.doi.org/10.1038/srep17407

Ejemplares similares

Neural Stem Cells Engineered to Express Three Therapeutic Factors Mediate Recovery from Chronic Stage CNS Autoimmunity
por: Li, Xing, et al.
Publicado: (2016)

Interferon regulatory factor (IRF) 3 is critical for the development of experimental autoimmune encephalomyelitis
por: Fitzgerald, Denise C, et al.
Publicado: (2014)

Combination Therapy With Fingolimod and Neural Stem Cells Promotes Functional Myelination in vivo Through a Non-immunomodulatory Mechanism
por: Zhang, Yuan, et al.
Publicado: (2019)

Corrigendum: Combination therapy with fingolimod and neural stem cells promotes functional myelination in vivo through a non-immunomodulatory mechanism
por: Zhang, Yuan, et al.
Publicado: (2022)

Mdivi-1, a mitochondrial fission inhibitor, modulates T helper cells and suppresses the development of experimental autoimmune encephalomyelitis
por: Li, Yan-Hua, et al.
Publicado: (2019)

A serine protease inhibitor induces type 1 regulatory T cells through IFN-γ/STAT1 signaling
por: Safavi, Farinaz, et al.
Publicado: (2020)

Induction of Peripheral Tolerance in Ongoing Autoimmune Inflammation Requires Interleukin 27 Signaling in Dendritic Cells
por: Thomé, Rodolfo, et al.
Publicado: (2017)

Functional interleukin-17 receptor A is expressed in central nervous system glia and upregulated in experimental autoimmune encephalomyelitis
por: Sarma, Jayasri Das, et al.
Publicado: (2009)

Bone marrow dendritic cells deficient for CD40 and IL-23p19 are tolerogenic in vitro
por: Kalantari, Tahereh, et al.
Publicado: (2020)

SIRT1 inactivation switches reactive astrocytes to an antiinflammatory phenotype in CNS autoimmunity
por: Zhang, Weifeng, et al.
Publicado: (2022)

Mechanism of gut microbiota and Axl/SOCS3 in experimental autoimmune encephalomyelitis
por: Li, Xiao-Ling, et al.
Publicado: (2019)

Transcription Factor RUNX3 Mediates Plasticity of ThGM Cells Toward Th1 Phenotype
por: Rasouli, Javad, et al.
Publicado: (2022)

Comprehensive Analysis of the Immune and Stromal Compartments of the CNS in EAE Mice Reveal Pathways by Which Chloroquine Suppresses Neuroinflammation
por: Thome, Rodolfo, et al.
Publicado: (2020)

Chloroquine reduces Th17 cell differentiation by stimulating T-bet expression in T cells
por: Thome, Rodolfo, et al.
Publicado: (2020)

Role of SOCS2 in the Regulation of Immune Response and Development of the Experimental Autoimmune Encephalomyelitis
por: Cramer, Allysson, et al.
Publicado: (2019)

CRISPR-mediated rapid generation of neural cell-specific knockout mice facilitates research in neurophysiology and pathology
por: Xiao, Dan, et al.
Publicado: (2021)

GATA1 controls numbers of hematopoietic progenitors and their response to autoimmune neuroinflammation
por: Hwang, Daniel, et al.
Publicado: (2022)

CSF-1 maintains pathogenic but not homeostatic myeloid cells in the central nervous system during autoimmune neuroinflammation
por: Hwang, Daniel, et al.
Publicado: (2022)

Interferon-γ/Interleukin-27 Axis Induces Programmed Death Ligand 1 Expression in Monocyte-Derived Dendritic Cells and Restores Immune Tolerance in Central Nervous System Autoimmunity
por: Casella, Giacomo, et al.
Publicado: (2020)

Distinct Role of IL-27 in Immature and LPS-Induced Mature Dendritic Cell-Mediated Development of CD4(+) CD127(+)3G11(+) Regulatory T Cell Subset
por: Zhou, Fang, et al.
Publicado: (2018)

IFN-β Acts on Monocytes to Ameliorate CNS Autoimmunity by Inhibiting Proinflammatory Cross-Talk Between Monocytes and Th Cells
por: Rasouli, Javad, et al.
Publicado: (2021)

Rapamycin Alleviates the Symptoms of Multiple Sclerosis in Experimental Autoimmune Encephalomyelitis (EAE) Through Mediating the TAM-TLRs-SOCS Pathway
por: Li, Xiao-ling, et al.
Publicado: (2020)

Roles of GM-CSF in the Pathogenesis of Autoimmune Diseases: An Update
por: Lotfi, Noushin, et al.
Publicado: (2019)

Carnosol Modulates Th17 Cell Differentiation and Microglial Switch in Experimental Autoimmune Encephalomyelitis
por: Li, Xing, et al.
Publicado: (2018)

Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice
por: Salem, Mohammad, et al.
Publicado: (2011)

Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis
por: Zhang, Su, et al.
Publicado: (2013)

Nasal delivery of Fasudil‐modified immune cells exhibits therapeutic potential in experimental autoimmune encephalomyelitis
por: Guo, Shang‐De, et al.
Publicado: (2019)

Potential roles of extracellular vesicles in the pathophysiology, diagnosis, and treatment of autoimmune diseases
por: Tian, Jing, et al.
Publicado: (2020)

Lactobacillus acidipiscis Induced Regulatory Gamma Delta T Cells and Attenuated Experimental Autoimmune Encephalomyelitis
por: Ren, Saisai, et al.
Publicado: (2021)

Chloroquine Treatment Enhances Regulatory T Cells and Reduces the Severity of Experimental Autoimmune Encephalomyelitis
por: Thomé, Rodolfo, et al.
Publicado: (2013)

Dysregulated follicular regulatory T cells and antibody responses exacerbate experimental autoimmune encephalomyelitis
por: Luo, Lin, et al.
Publicado: (2021)

Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis
por: Dang, Shipeng, et al.
Publicado: (2014)

Amelioration of Experimental Autoimmune Encephalomyelitis by Anatabine
por: Paris, Daniel, et al.
Publicado: (2013)

Environmental Influences in Experimental Autoimmune Encephalomyelitis
por: Constantinescu, Cris S
Publicado: (2005)

The primate autoimmune encephalomyelitis model; a bridge between mouse and man
por: ‘t Hart, Bert A, et al.
Publicado: (2015)

Erythropoietin and autoimmune neuroinflammation: lessons from experimental autoimmune encephalomyelitis and experimental autoimmune neuritis
por: Shin, Taekyun, et al.
Publicado: (2012)

Therapeutic Potential of Pien Tze Huang on Experimental Autoimmune Encephalomyelitis Rat
por: Qiu, Xuemei, et al.
Publicado: (2018)

SOCS, Inflammation, and Autoimmunity
por: Yoshimura, Akihiko, et al.
Publicado: (2012)

Parthenolide Suppresses T Helper 17 and Alleviates Experimental Autoimmune Encephalomyelitis
por: Zhang, Zhihui, et al.
Publicado: (2022)

Angiogenesis in multiple sclerosis and experimental autoimmune encephalomyelitis
por: Girolamo, Francesco, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_tbqqvlprtg7m7c0kbu3a84lo2f