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Double filtration plasmapheresis in a dog with multiple myeloma and hyperviscosity syndrome
A 12 year old, 38 kg, mix-breed, intact male dog presented with a 20 day history of clinical signs consistent with hyperviscosity syndrome secondary to multiple myeloma. The dog received three double filtration plasmapheresis treatments on day 0, 7 and 22 after presentation. A significant (p<0.05...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Faculty of Veterinary Medicine, University of Tripoli and Libyan Authority for Research, Science and Technology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663801/ https://www.ncbi.nlm.nih.gov/pubmed/26623375 |
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author | Lippi, I. Perondi, F. Ross, S.J. Marchetti, V. Lubas, G. Guidi, G. |
author_facet | Lippi, I. Perondi, F. Ross, S.J. Marchetti, V. Lubas, G. Guidi, G. |
author_sort | Lippi, I. |
collection | PubMed |
description | A 12 year old, 38 kg, mix-breed, intact male dog presented with a 20 day history of clinical signs consistent with hyperviscosity syndrome secondary to multiple myeloma. The dog received three double filtration plasmapheresis treatments on day 0, 7 and 22 after presentation. A significant (p<0.05) reduction in serum total protein, alpha-2 and gamma globulins was found following each treatment. These reductions were accompanied by a complete resolution, although temporary, of the clinical signs of hyperviscosity syndrome. The present study reported for the first time the use of double filtration plasmapheresis to reduce clinical signs of hyperviscosity syndrome in a dog with multiple myeloma. |
format | Online Article Text |
id | pubmed-4663801 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Faculty of Veterinary Medicine, University of Tripoli and Libyan Authority for Research, Science and Technology |
record_format | MEDLINE/PubMed |
spelling | pubmed-46638012015-11-30 Double filtration plasmapheresis in a dog with multiple myeloma and hyperviscosity syndrome Lippi, I. Perondi, F. Ross, S.J. Marchetti, V. Lubas, G. Guidi, G. Open Vet J Case Report A 12 year old, 38 kg, mix-breed, intact male dog presented with a 20 day history of clinical signs consistent with hyperviscosity syndrome secondary to multiple myeloma. The dog received three double filtration plasmapheresis treatments on day 0, 7 and 22 after presentation. A significant (p<0.05) reduction in serum total protein, alpha-2 and gamma globulins was found following each treatment. These reductions were accompanied by a complete resolution, although temporary, of the clinical signs of hyperviscosity syndrome. The present study reported for the first time the use of double filtration plasmapheresis to reduce clinical signs of hyperviscosity syndrome in a dog with multiple myeloma. Faculty of Veterinary Medicine, University of Tripoli and Libyan Authority for Research, Science and Technology 2015 2015-08-07 /pmc/articles/PMC4663801/ /pubmed/26623375 Text en Copyright: © Open Veterinary Journal http://creativecommons.org/licenses/by-nc-sa/4.0 Open Veterinary Journal is licensed under a Creative Commons Attribution 4.0 International License. |
spellingShingle | Case Report Lippi, I. Perondi, F. Ross, S.J. Marchetti, V. Lubas, G. Guidi, G. Double filtration plasmapheresis in a dog with multiple myeloma and hyperviscosity syndrome |
title | Double filtration plasmapheresis in a dog with multiple myeloma and hyperviscosity syndrome |
title_full | Double filtration plasmapheresis in a dog with multiple myeloma and hyperviscosity syndrome |
title_fullStr | Double filtration plasmapheresis in a dog with multiple myeloma and hyperviscosity syndrome |
title_full_unstemmed | Double filtration plasmapheresis in a dog with multiple myeloma and hyperviscosity syndrome |
title_short | Double filtration plasmapheresis in a dog with multiple myeloma and hyperviscosity syndrome |
title_sort | double filtration plasmapheresis in a dog with multiple myeloma and hyperviscosity syndrome |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663801/ https://www.ncbi.nlm.nih.gov/pubmed/26623375 |
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