Phenytoin-induced acute hypersensitivity pneumonitis

Lungs are target organs for toxic effects of various drugs due to many reasons. Diphenylhydantoin (DPH) is reported to have many extrapulmonary side effects. We are presenting a case of acute hypersensitivity pneumonitis (HP) secondary to DPH, presenting with respiratory failure. Acute HP with respi...

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Autores principales: Periwal, Pallavi, Joshi, Sharad, Gothi, Rajesh, Talwar, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663873/
https://www.ncbi.nlm.nih.gov/pubmed/26664176
http://dx.doi.org/10.4103/0970-2113.168126
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author Periwal, Pallavi
Joshi, Sharad
Gothi, Rajesh
Talwar, Deepak
author_facet Periwal, Pallavi
Joshi, Sharad
Gothi, Rajesh
Talwar, Deepak
author_sort Periwal, Pallavi
collection PubMed
description Lungs are target organs for toxic effects of various drugs due to many reasons. Diphenylhydantoin (DPH) is reported to have many extrapulmonary side effects. We are presenting a case of acute hypersensitivity pneumonitis (HP) secondary to DPH, presenting with respiratory failure. Acute HP with respiratory failure is an uncommon drug side effect of the DPH therapy and is a diagnosis of exclusion. It requires detailed workup and exclusion of other causes along with evidence of improvement in the patient's condition after withholding DPH.
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spelling pubmed-46638732015-12-10 Phenytoin-induced acute hypersensitivity pneumonitis Periwal, Pallavi Joshi, Sharad Gothi, Rajesh Talwar, Deepak Lung India Case Report Lungs are target organs for toxic effects of various drugs due to many reasons. Diphenylhydantoin (DPH) is reported to have many extrapulmonary side effects. We are presenting a case of acute hypersensitivity pneumonitis (HP) secondary to DPH, presenting with respiratory failure. Acute HP with respiratory failure is an uncommon drug side effect of the DPH therapy and is a diagnosis of exclusion. It requires detailed workup and exclusion of other causes along with evidence of improvement in the patient's condition after withholding DPH. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4663873/ /pubmed/26664176 http://dx.doi.org/10.4103/0970-2113.168126 Text en Copyright: © Lung India http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Periwal, Pallavi
Joshi, Sharad
Gothi, Rajesh
Talwar, Deepak
Phenytoin-induced acute hypersensitivity pneumonitis
title Phenytoin-induced acute hypersensitivity pneumonitis
title_full Phenytoin-induced acute hypersensitivity pneumonitis
title_fullStr Phenytoin-induced acute hypersensitivity pneumonitis
title_full_unstemmed Phenytoin-induced acute hypersensitivity pneumonitis
title_short Phenytoin-induced acute hypersensitivity pneumonitis
title_sort phenytoin-induced acute hypersensitivity pneumonitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663873/
https://www.ncbi.nlm.nih.gov/pubmed/26664176
http://dx.doi.org/10.4103/0970-2113.168126
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AT talwardeepak phenytoininducedacutehypersensitivitypneumonitis

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