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Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors

Genome-wide association studies have identified over 70 single-nucleotide polymorphisms (SNPs) associated with breast cancer. A subset of these SNPs are associated with quantitative expression of nearby genes, but the functional effects of the majority remain unknown. We hypothesized that some risk...

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Detalles Bibliográficos
Autores principales:	Caswell, Jennifer L., Camarda, Roman, Zhou, Alicia Y., Huntsman, Scott, Hu, Donglei, Brenner, Steven E., Zaitlen, Noah, Goga, Andrei, Ziv, Elad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Association Studies Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664170/ https://www.ncbi.nlm.nih.gov/pubmed/26472073 http://dx.doi.org/10.1093/hmg/ddv432

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