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Methylation quantitative trait locus analysis of osteoarthritis links epigenetics with genetic risk

Osteoarthritis (OA) is a common, painful and debilitating disease of articulating joints resulting from the age-associated loss of cartilage. Well-powered genetic studies have identified a number of DNA polymorphisms that are associated with OA susceptibility. Like most complex trait loci, these OA...

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Detalles Bibliográficos
Autores principales:	Rushton, Michael D., Reynard, Louise N., Young, David A., Shepherd, Colin, Aubourg, Guillaume, Gee, Fiona, Darlay, Rebecca, Deehan, David, Cordell, Heather J., Loughlin, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Association Studies Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664171/ https://www.ncbi.nlm.nih.gov/pubmed/26464490 http://dx.doi.org/10.1093/hmg/ddv433

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