Studying the Impact of Presence of Alpha Acid Glycoprotein and Protein Glycoprotein in Chronic Myeloid Leukemia Patients Treated with Imatinib Mesylate in the State of Qatar

Despite the efficacy of imatinib mesylate (IM) in treating chronic myeloid leukemia (CML), there is a high degree of resistance. Alpha- 1-acid glycoprotein may reduce drug efficacy through its ability to interact with IM and blocks it from reaching its target, while protein glycoprotein (PGP) may re...

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Detalles Bibliográficos
Autores principales: Al-Dewik, Nader I., Jewell, Andrew P., Yassin, Mohammed A., Morsi, Hisham M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664201/
https://www.ncbi.nlm.nih.gov/pubmed/26640393
http://dx.doi.org/10.4137/BIC.S31427

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