Cargando…
Dancing through Life: Molecular Dynamics Simulations and Network-Centric Modeling of Allosteric Mechanisms in Hsp70 and Hsp110 Chaperone Proteins
Hsp70 and Hsp110 chaperones play an important role in regulating cellular processes that involve protein folding and stabilization, which are essential for the integrity of signaling networks. Although many aspects of allosteric regulatory mechanisms in Hsp70 and Hsp110 chaperones have been extensiv...
Autores principales: | Stetz, Gabrielle, Verkhivker, Gennady M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664246/ https://www.ncbi.nlm.nih.gov/pubmed/26619280 http://dx.doi.org/10.1371/journal.pone.0143752 |
Ejemplares similares
-
Computational Analysis of Residue Interaction Networks and Coevolutionary Relationships in the Hsp70 Chaperones: A Community-Hopping Model of Allosteric Regulation and Communication
por: Stetz, Gabrielle, et al.
Publicado: (2017) -
Dissecting Structure-Encoded Determinants of Allosteric Cross-Talk between Post-Translational Modification Sites in the Hsp90 Chaperones
por: Stetz, Gabrielle, et al.
Publicado: (2018) -
Ensemble-based modeling and rigidity decomposition of allosteric interaction networks and communication pathways in cyclin-dependent kinases: Differentiating kinase clients of the Hsp90-Cdc37 chaperone
por: Stetz, Gabrielle, et al.
Publicado: (2017) -
Hsp110 Chaperones Control Client Fate Determination in the Hsp70–Hsp90 Chaperone System
por: Mandal, Atin K., et al.
Publicado: (2010) -
Pathways of allosteric regulation in Hsp70 chaperones
por: Kityk, Roman, et al.
Publicado: (2015)