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Increased Susceptibility of Humanized NSG Mice to Panton-Valentine Leukocidin and Staphylococcus aureus Skin Infection

Staphylococcus aureus is a leading cause of skin and soft-tissue infections worldwide. Mice are the most commonly used animals for modeling human staphylococcal infections. However a supra-physiologic S. aureus inoculum is required to establish gross murine skin pathology. Moreover, many staphylococ...

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Detalles Bibliográficos
Autores principales: Tseng, Ching Wen, Biancotti, Juan Carlos, Berg, Bethany L., Gate, David, Kolar, Stacey L., Müller, Sabrina, Rodriguez, Maria D., Rezai-Zadeh, Kavon, Fan, Xuemo, Beenhouwer, David O., Town, Terrence, Liu, George Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664407/
https://www.ncbi.nlm.nih.gov/pubmed/26618545
http://dx.doi.org/10.1371/journal.ppat.1005292