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Increased Susceptibility of Humanized NSG Mice to Panton-Valentine Leukocidin and Staphylococcus aureus Skin Infection
Staphylococcus aureus is a leading cause of skin and soft-tissue infections worldwide. Mice are the most commonly used animals for modeling human staphylococcal infections. However a supra-physiologic S. aureus inoculum is required to establish gross murine skin pathology. Moreover, many staphylococ...
Autores principales: | Tseng, Ching Wen, Biancotti, Juan Carlos, Berg, Bethany L., Gate, David, Kolar, Stacey L., Müller, Sabrina, Rodriguez, Maria D., Rezai-Zadeh, Kavon, Fan, Xuemo, Beenhouwer, David O., Town, Terrence, Liu, George Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664407/ https://www.ncbi.nlm.nih.gov/pubmed/26618545 http://dx.doi.org/10.1371/journal.ppat.1005292 |
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