Cargando…

Loss of Ifnar1 in Pancreatic Acinar Cells Ameliorates the Disease Course of Acute Pancreatitis

Type I interferon constitutes an essential component of the combinational therapy against viral disease. Acute pancreatitis is one side effect of type I interferon-based therapy, implying that activation of type I interferon signaling affects the homeostasis and integrity of pancreatic acinar cells....

Descripción completa

Detalles Bibliográficos
Autores principales:	Miller, Katharina J., Raulefs, Susanne, Kong, Bo, Steiger, Katja, Regel, Ivonne, Gewies, Andreas, Kleeff, Jörg, Michalski, Christoph W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664425/ https://www.ncbi.nlm.nih.gov/pubmed/26618925 http://dx.doi.org/10.1371/journal.pone.0143735

Ejemplares similares

Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells
por: Benitz, Simone, et al.
Publicado: (2015)

Pancreas-specific activation of mTOR and loss of p53 induce tumors reminiscent of acinar cell carcinoma
por: Kong, Bo, et al.
Publicado: (2015)

Hypoxia-induced endoplasmic reticulum stress characterizes a necrotic phenotype of pancreatic cancer
por: Kong, Bo, et al.
Publicado: (2015)

Molecular, morphological and survival analysis of 177 resected pancreatic ductal adenocarcinomas (PDACs): Identification of prognostic subtypes
por: Schlitter, Anna Melissa, et al.
Publicado: (2017)

In vivo functional dissection of a context-dependent role for Hif1α in pancreatic tumorigenesis
por: Cheng, T, et al.
Publicado: (2016)

Syndecan-2 promotes perineural invasion and cooperates with K-ras to induce an invasive pancreatic cancer cell phenotype
por: De Oliveira, Tiago, et al.
Publicado: (2012)

Next-generation sequencing reveals novel differentially regulated mRNAs, lncRNAs, miRNAs, sdRNAs and a piRNA in pancreatic cancer
por: Müller, Sören, et al.
Publicado: (2015)

Erratum to: Next-generation sequencing reveals novel differentially regulated mRNAs, lncRNAs, miRNAs, sdRNAs and a piRNA in pancreatic cancer
por: Müller, Sören, et al.
Publicado: (2015)

Periostin and tumor-stroma interactions in non-small cell lung cancer
por: Nitsche, Ulrich, et al.
Publicado: (2016)

Glycemic Variability Promotes Both Local Invasion and Metastatic Colonization by Pancreatic Ductal Adenocarcinoma
por: Jian, Ziying, et al.
Publicado: (2018)

Pancreatic Acinar Cell Carcinoma
por: Béchade, Dominique, et al.
Publicado: (2016)

Surgery for Cystic Pancreatic Lesions in the Post-Sendai Era: A Single Institution Experience
por: Kleeff, Jörg, et al.
Publicado: (2015)

Overview on how oncogenic Kras promotes pancreatic carcinogenesis by inducing low intracellular ROS levels
por: Kong, Bo, et al.
Publicado: (2013)

Amelioration of Experimental Acute Pancreatitis with Dachengqi Decoction via Regulation of Necrosis-Apoptosis Switch in the Pancreatic Acinar Cell
por: Wang, Jia, et al.
Publicado: (2012)

Activation of AMPK ameliorates acute severe pancreatitis by suppressing pancreatic acinar cell necroptosis in obese mice models
por: Wang, Kunlei, et al.
Publicado: (2023)

Do we need sequential local therapy following neoadjuvant chemotherapy for locally advanced pancreatic cancer?
por: Kleeff, Jörg, et al.
Publicado: (2019)

Regulated Exocytosis in the Pancreatic Acinar Cell
por: Jamieson, J.D., et al.
Publicado: (1997)

Discussion: Pancreatic Acinar Cell Pathophysiology
por: Gorelick, Fred S.
Publicado: (1992)

SULFATE METABOLISM IN PANCREATIC ACINAR CELLS
por: Berg, Norton B., et al.
Publicado: (1971)

Palliative Interventional and Surgical Therapy for Unresectable Pancreatic Cancer
por: Assfalg, Volker, et al.
Publicado: (2011)

Current Strategies and Future Perspectives for Precision Medicine in Pancreatic Cancer
por: Regel, Ivonne, et al.
Publicado: (2020)

Inflammatory macrophages in pancreatic acinar cell metaplasia and initiation of pancreatic cancer
por: Liou, Geou-Yarh, et al.
Publicado: (2015)

RESTITUTION OF PANCREATIC ACINAR CELLS FOLLOWING ETHIONINE
por: Herman, Lawrence, et al.
Publicado: (1962)

Papillocystic Variant of Acinar Cell Pancreatic Carcinoma
por: Radhi, Jasim, et al.
Publicado: (2010)

Pancreatic acinar cell carcinoma–induced panniculitis
por: Singh, Sanminder, et al.
Publicado: (2018)

Zonation of Pancreatic Acinar Cells in Diabetic Mice
por: Egozi, Adi, et al.
Publicado: (2020)

Esophageal Pancreatic Acinar Heterotopia: Premalignant or Benign
por: Mills, Krystal, et al.
Publicado: (2022)

miR-29a-deficiency does not modify the course of murine pancreatic acinar carcinoma
por: Dooley, James, et al.
Publicado: (2017)

TGF-β1 promotes acinar to ductal metaplasia of human pancreatic acinar cells
por: Liu, Jun, et al.
Publicado: (2016)

Association of IFNAR1 and IFNAR2 with COVID-19 severity
por: Yaugel-Novoa, Melyssa, et al.
Publicado: (2023)

BGLAP is expressed in pancreatic cancer cells and increases their growth and invasion
por: Kayed, Hany, et al.
Publicado: (2007)

Necro-inflammatory response of pancreatic acinar cells in the pathogenesis of acute alcoholic pancreatitis
por: Gu, H, et al.
Publicado: (2013)

PD2/Paf1 depletion in pancreatic acinar cells promotes acinar-to-ductal metaplasia
por: Dey, Parama, et al.
Publicado: (2014)

Cholesterol Metabolism in Pancreatic Cancer
por: Rebelo, Artur, et al.
Publicado: (2023)

CHANGES IN PANCREATIC ACINAR CELLS DURING PROTEIN DEPRIVATION
por: Weisblum, Bernard, et al.
Publicado: (1962)

Polarization Optical Properties of the Pancreatic Acinar Cell of the Mouse
por: Munger, Bryce L.
Publicado: (1958)

NF-kappaB and cytokines in pancreatic acinar cells.
por: Kim, H, et al.
Publicado: (2000)

Acinar Cell Carcinoma: A Rare Pancreatic Malignancy
por: Chaudhary, Poras, et al.
Publicado: (2013)

Snail1 is required for the maintenance of the pancreatic acinar phenotype
por: Loubat-Casanovas, Jordina, et al.
Publicado: (2015)

Pancreatic acinar differentiation is guided by differential laminin deposition
por: Heymans, Charlotte, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_m6p1lin5bk7obm3jlbalik54mi