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Autoantibodies against Cytochrome P450 Side-Chain Cleavage Enzyme in Dogs (Canis lupus familiaris) Affected with Hypoadrenocorticism (Addison’s Disease)

Canine hypoadrenocorticism likely arises from immune-mediated destruction of adrenocortical tissue, leading to glucocorticoid and mineralocorticoid deficiency. In humans with autoimmune Addison’s disease (AAD) or autoimmune polyendocrine syndrome (APS), circulating autoantibodies have been demonstra...

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Detalles Bibliográficos
Autores principales:	Boag, Alisdair M., Christie, Michael R., McLaughlin, Kerry A., Syme, Harriet M., Graham, Peter, Catchpole, Brian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664467/ https://www.ncbi.nlm.nih.gov/pubmed/26618927 http://dx.doi.org/10.1371/journal.pone.0143458

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