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Serological Survey for Avian Influenza in Turkeys in Three States of Southwest Nigeria

Since the first outbreak of avian influenza (AI) in Nigeria in 2006, there has been continuous monitoring of the disease in chickens with little attention given to turkeys. As part of on-going surveillance for AI in southwest Nigeria, we used a competitive ELISA to detect anti-AI virus antibodies in...

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Autores principales: Oluwayelu, Daniel Oladimeji, Aiki-Raji, Comfort Oluladun, Adigun, Oladunni Taiwo, Olofintuyi, Opeyemi Kazeem, Adebiyi, Adebowale Idris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664809/
https://www.ncbi.nlm.nih.gov/pubmed/26664747
http://dx.doi.org/10.1155/2015/787890
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author Oluwayelu, Daniel Oladimeji
Aiki-Raji, Comfort Oluladun
Adigun, Oladunni Taiwo
Olofintuyi, Opeyemi Kazeem
Adebiyi, Adebowale Idris
author_facet Oluwayelu, Daniel Oladimeji
Aiki-Raji, Comfort Oluladun
Adigun, Oladunni Taiwo
Olofintuyi, Opeyemi Kazeem
Adebiyi, Adebowale Idris
author_sort Oluwayelu, Daniel Oladimeji
collection PubMed
description Since the first outbreak of avian influenza (AI) in Nigeria in 2006, there has been continuous monitoring of the disease in chickens with little attention given to turkeys. As part of on-going surveillance for AI in southwest Nigeria, we used a competitive ELISA to detect anti-AI virus antibodies in 520 turkey sera obtained from poultry farms in Oyo, Osun, and Ondo states while haemagglutination inhibiting antibodies against low pathogenic AI viruses (LPAIVs) were detected using H3N8 and H5N2 subtype-specific antigens. The overall seroprevalence obtained by ELISA was 4.4% (23/520). Of the 23 ELISA-positive samples, 18 were positive for anti-AIV H3N8 antibodies only and four were positive for both anti-AIV H3N8 and H5N2 antibodies indicating a mixed infection, while five were negative for antibodies to either of the two AIV subtypes. Considering that turkeys have been implicated as a mixing vessel for generating influenza virus reassortants of human and avian origin, the detection of antibodies to LPAIV H3N8 and H5N2 in these turkeys is of public health concern. We advocate further studies to determine the potential role of turkeys in the zoonotic transmission of AIVs in Nigeria. Additionally, the practice of rearing turkeys with chickens should be discouraged.
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spelling pubmed-46648092015-12-09 Serological Survey for Avian Influenza in Turkeys in Three States of Southwest Nigeria Oluwayelu, Daniel Oladimeji Aiki-Raji, Comfort Oluladun Adigun, Oladunni Taiwo Olofintuyi, Opeyemi Kazeem Adebiyi, Adebowale Idris Influenza Res Treat Research Article Since the first outbreak of avian influenza (AI) in Nigeria in 2006, there has been continuous monitoring of the disease in chickens with little attention given to turkeys. As part of on-going surveillance for AI in southwest Nigeria, we used a competitive ELISA to detect anti-AI virus antibodies in 520 turkey sera obtained from poultry farms in Oyo, Osun, and Ondo states while haemagglutination inhibiting antibodies against low pathogenic AI viruses (LPAIVs) were detected using H3N8 and H5N2 subtype-specific antigens. The overall seroprevalence obtained by ELISA was 4.4% (23/520). Of the 23 ELISA-positive samples, 18 were positive for anti-AIV H3N8 antibodies only and four were positive for both anti-AIV H3N8 and H5N2 antibodies indicating a mixed infection, while five were negative for antibodies to either of the two AIV subtypes. Considering that turkeys have been implicated as a mixing vessel for generating influenza virus reassortants of human and avian origin, the detection of antibodies to LPAIV H3N8 and H5N2 in these turkeys is of public health concern. We advocate further studies to determine the potential role of turkeys in the zoonotic transmission of AIVs in Nigeria. Additionally, the practice of rearing turkeys with chickens should be discouraged. Hindawi Publishing Corporation 2015 2015-11-17 /pmc/articles/PMC4664809/ /pubmed/26664747 http://dx.doi.org/10.1155/2015/787890 Text en Copyright © 2015 Daniel Oladimeji Oluwayelu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Oluwayelu, Daniel Oladimeji
Aiki-Raji, Comfort Oluladun
Adigun, Oladunni Taiwo
Olofintuyi, Opeyemi Kazeem
Adebiyi, Adebowale Idris
Serological Survey for Avian Influenza in Turkeys in Three States of Southwest Nigeria
title Serological Survey for Avian Influenza in Turkeys in Three States of Southwest Nigeria
title_full Serological Survey for Avian Influenza in Turkeys in Three States of Southwest Nigeria
title_fullStr Serological Survey for Avian Influenza in Turkeys in Three States of Southwest Nigeria
title_full_unstemmed Serological Survey for Avian Influenza in Turkeys in Three States of Southwest Nigeria
title_short Serological Survey for Avian Influenza in Turkeys in Three States of Southwest Nigeria
title_sort serological survey for avian influenza in turkeys in three states of southwest nigeria
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664809/
https://www.ncbi.nlm.nih.gov/pubmed/26664747
http://dx.doi.org/10.1155/2015/787890
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