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iTRAQ proteomic analysis of extracellular matrix remodeling in aortic valve disease
Degenerative aortic stenosis (AS) is the most common worldwide cause of valve replacement. The aortic valve is a thin, complex, layered connective tissue with compartmentalized extracellular matrix (ECM) produced by specialized cell types, which directs blood flow in one direction through the heart....
Autores principales: | Martin-Rojas, Tatiana, Mourino-Alvarez, Laura, Alonso-Orgaz, Sergio, Rosello-Lleti, Esther, Calvo, Enrique, Lopez-Almodovar, Luis Fernando, Rivera, Miguel, Padial, Luis R., Lopez, Juan Antonio, Cuesta, Fernando de la, Barderas, Maria G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664895/ https://www.ncbi.nlm.nih.gov/pubmed/26620461 http://dx.doi.org/10.1038/srep17290 |
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