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The standalone aminopeptidase PepN catalyzes the maturation of blasticidin S from leucylblasticidin S
The peptidyl nucleoside blasticidin S (BS) isolated from Streptomyces griseochromogenes was the first non-mercurial fungicide used on a large scale to prevent rice blast. In the biosynthesis of BS, leucylblasticidin S (LBS) was suggested as the penultimate metabolite with 20-fold less inhibitory act...
Autores principales: | Yu, Guiyang, Li, Li, Liu, Xiangyang, Liu, Guang, Deng, Zixin, Zabriskie, Mark T., Jiang, Ming, He, Xinyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664946/ https://www.ncbi.nlm.nih.gov/pubmed/26621790 http://dx.doi.org/10.1038/srep17641 |
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