Inhibition of Osteoclastogenesis and Bone Resorption in vitro and in vivo by a prenylflavonoid xanthohumol from hops

Excessive RANKL signaling leads to superfluous osteoclast formation and bone resorption, is widespread in the pathologic bone loss and destruction. Therefore, targeting RANKL or its signaling pathway has been a promising and successful strategy for this osteoclast-related diseases. In this study, we...

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Detalles Bibliográficos
Autores principales: Li, Jing, Zeng, Li, Xie, Juan, Yue, Zhiying, Deng, Huayun, Ma, Xueyun, Zheng, Chunbing, Wu, Xiushan, Luo, Jian, Liu, Mingyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664947/
https://www.ncbi.nlm.nih.gov/pubmed/26620037
http://dx.doi.org/10.1038/srep17605

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