RBFOX3/NeuN is Required for Hippocampal Circuit Balance and Function

RBFOX3 mutations are linked to epilepsy and cognitive impairments, but the underlying pathophysiology of these disorders is poorly understood. Here we report replication of human symptoms in a mouse model with disrupted Rbfox3. Rbfox3 knockout mice displayed increased seizure susceptibility and decr...

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Detalles Bibliográficos
Autores principales: Wang, Han-Ying, Hsieh, Pei-Fen, Huang, De-Fong, Chin, Pey-Shyuan, Chou, Chih-Hsuan, Tung, Chun-Che, Chen, Shin-Yuan, Lee, Li-Jen, Gau, Susan Shur-Fen, Huang, Hsien-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664964/
https://www.ncbi.nlm.nih.gov/pubmed/26619789
http://dx.doi.org/10.1038/srep17383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664964/
https://www.ncbi.nlm.nih.gov/pubmed/26619789
http://dx.doi.org/10.1038/srep17383

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