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Development of Alendronate-conjugated Poly (lactic-co-glycolic acid)-Dextran Nanoparticles for Active Targeting of Cisplatin in Osteosarcoma
In this study, we developed a novel poly (lactic-co-glycolic acid)-dextran (PLD)-based nanodelivery system to enhance the anticancer potential of cisplatin (CDDP) in osteosarcoma cells. A nanosized CDDP-loaded PLGA-DX nanoparticle (PLD/CDDP) controlled the release rate of CDDP up to 48 h. In vitro c...
Autores principales: | Liu, Ping, Sun, Liang, Zhou, Dong-sheng, Zhang, Peng, Wang, Yong-hui, Li, Dong, Li, Qing-hu, Feng, Rong-jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664968/ https://www.ncbi.nlm.nih.gov/pubmed/26619950 http://dx.doi.org/10.1038/srep17387 |
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