Acetylation of glucokinase regulatory protein decreases glucose metabolism by suppressing glucokinase activity

Glucokinase (GK), mainly expressed in the liver and pancreatic β-cells, is critical for maintaining glucose homeostasis. GK expression and kinase activity, respectively, are both modulated at the transcriptional and post-translational levels. Post-translationally, GK is regulated by binding the gluc...

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Detalles Bibliográficos
Autores principales: Park, Joo-Man, Kim, Tae-Hyun, Jo, Seong-Ho, Kim, Mi-Young, Ahn, Yong-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664969/
https://www.ncbi.nlm.nih.gov/pubmed/26620281
http://dx.doi.org/10.1038/srep17395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664969/
https://www.ncbi.nlm.nih.gov/pubmed/26620281
http://dx.doi.org/10.1038/srep17395

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