Chikungunya Virus Replication in Salivary Glands of the Mosquito Aedes albopictus

Chikungunya virus (CHIKV) is an emerging arbovirus transmitted to humans by mosquitoes such as Aedes albopictus. To be transmitted, CHIKV must replicate in the mosquito midgut, then disseminate in the hemocele and infect the salivary glands before being released in saliva. We have developed a standa...

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Autores principales: Vega-Rúa, Anubis, Schmitt, Christine, Bonne, Isabelle, Krijnse Locker, Jacomine, Failloux, Anna-Bella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664990/
https://www.ncbi.nlm.nih.gov/pubmed/26593936
http://dx.doi.org/10.3390/v7112917
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author Vega-Rúa, Anubis
Schmitt, Christine
Bonne, Isabelle
Krijnse Locker, Jacomine
Failloux, Anna-Bella
author_facet Vega-Rúa, Anubis
Schmitt, Christine
Bonne, Isabelle
Krijnse Locker, Jacomine
Failloux, Anna-Bella
author_sort Vega-Rúa, Anubis
collection PubMed
description Chikungunya virus (CHIKV) is an emerging arbovirus transmitted to humans by mosquitoes such as Aedes albopictus. To be transmitted, CHIKV must replicate in the mosquito midgut, then disseminate in the hemocele and infect the salivary glands before being released in saliva. We have developed a standardized protocol to visualize viral particles in the mosquito salivary glands using transmission electron microscopy. Here we provide direct evidence for CHIKV replication and storage in Ae. albopictus salivary glands.
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spelling pubmed-46649902015-12-10 Chikungunya Virus Replication in Salivary Glands of the Mosquito Aedes albopictus Vega-Rúa, Anubis Schmitt, Christine Bonne, Isabelle Krijnse Locker, Jacomine Failloux, Anna-Bella Viruses Brief Report Chikungunya virus (CHIKV) is an emerging arbovirus transmitted to humans by mosquitoes such as Aedes albopictus. To be transmitted, CHIKV must replicate in the mosquito midgut, then disseminate in the hemocele and infect the salivary glands before being released in saliva. We have developed a standardized protocol to visualize viral particles in the mosquito salivary glands using transmission electron microscopy. Here we provide direct evidence for CHIKV replication and storage in Ae. albopictus salivary glands. MDPI 2015-11-17 /pmc/articles/PMC4664990/ /pubmed/26593936 http://dx.doi.org/10.3390/v7112917 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Vega-Rúa, Anubis
Schmitt, Christine
Bonne, Isabelle
Krijnse Locker, Jacomine
Failloux, Anna-Bella
Chikungunya Virus Replication in Salivary Glands of the Mosquito Aedes albopictus
title Chikungunya Virus Replication in Salivary Glands of the Mosquito Aedes albopictus
title_full Chikungunya Virus Replication in Salivary Glands of the Mosquito Aedes albopictus
title_fullStr Chikungunya Virus Replication in Salivary Glands of the Mosquito Aedes albopictus
title_full_unstemmed Chikungunya Virus Replication in Salivary Glands of the Mosquito Aedes albopictus
title_short Chikungunya Virus Replication in Salivary Glands of the Mosquito Aedes albopictus
title_sort chikungunya virus replication in salivary glands of the mosquito aedes albopictus
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664990/
https://www.ncbi.nlm.nih.gov/pubmed/26593936
http://dx.doi.org/10.3390/v7112917
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