SORBS2 transcription is activated by telomere position effect–over long distance upon telomere shortening in muscle cells from patients with facioscapulohumeral dystrophy

DNA is organized into complex three-dimensional chromatin structures, but how this spatial organization regulates gene expression remains a central question. These DNA/chromatin looping structures can range in size from 10–20 kb (enhancers/repressors) to many megabases during intra- and inter-chromo...

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Detalles Bibliográficos
Autores principales: Robin, Jérôme D., Ludlow, Andrew T., Batten, Kimberly, Gaillard, Marie-Cécile, Stadler, Guido, Magdinier, Frédérique, Wright, Woodring E., Shay, Jerry W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665000/
https://www.ncbi.nlm.nih.gov/pubmed/26359233
http://dx.doi.org/10.1101/gr.190660.115

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