Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites

Transcription factors (TFs) bind to thousands of DNA sequences in mammalian genomes, but most of these binding events appear to have no direct effect on gene expression. It is unclear why only a subset of TF bound sites are actively involved in transcriptional regulation. Moreover, the key genomic f...

Descripción completa

Detalles Bibliográficos
Autores principales: Savic, Daniel, Roberts, Brian S., Carleton, Julia B., Partridge, E. Christopher, White, Michael A., Cohen, Barak A., Cooper, Gregory M., Gertz, Jason, Myers, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665001/
https://www.ncbi.nlm.nih.gov/pubmed/26486725
http://dx.doi.org/10.1101/gr.191593.115

Ejemplares similares

Ejemplares similares